Copy number changes of target genes in chromosome 3q25.3-qter of esophageal squamous cell carcinoma: TP63 is amplified in early carcinogenesis but down-regulated as disease progressed

doi:10.3748/wjg.v11.i9.1267

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Mar 7, 2005 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Esophageal Cancer

World J Gastroenterol. Mar 7, 2005; 11(9): 1267-1272
Published online Mar 7, 2005. doi: 10.3748/wjg.v11.i9.1267

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Figure 4 In Q-PCR analysis of 60 EC-SCC tumors, patients with lymph node metastasis [LN (+)] have significantly lower copy number of TP63 in the primary tumor than those without lymph node metastasis [LN (-)] (2. 05 vs 3.08; P = 0.017).

Citation: Yen CC, Chen YJ, Pan CC, Lu KH, Chen PCH, Hsia JY, Chen JT, Wu YC, Hsu WH, Wang LS, Huang MH, Huang BS, Hu CP, Chen PM, Lin CH. Copy number changes of target genes in chromosome 3q25.3-qter of esophageal squamous cell carcinoma: TP63 is amplified in early carcinogenesis but down-regulated as disease progressed. World J Gastroenterol 2005; 11(9): 1267-1272
URL: https://www.wjgnet.com/1007-9327/full/v11/i9/1267.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i9.1267