A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis

Table 3 Effects of PN50 before and after treatment on the histologic parameters in CCK-induced acute pancreatitis (mean±SD).

	Group PS	Group CCK	Group PN50+CCK	Group CCK+PN50
Edema	0.1±0.067	0.955±0.045b	0.55±0.117bd	0.636 ± 0.097bd
Vascular Change	0.1±0.067	0.773± 0.079b	0.4±0.1ad	0.55 ± 0.05bc
Inflammation	0	0.591±0.061b	0.3±0.082bd	0.35 ± 0.076bc
Acinar necrosis	0	0.955±0.081b	0.45±0.09bd	0.65 ± 0.076bc
Calcification	0	0.125±0.065	0	0
Fat necrosis	0	0.167±0.071a	0.05±0.05	0.05±0.05

^aP<0.05,

^bP<0.01 vs group PS;

^cP<0.05,

^dP<0.01 vs group CCK.