Anti-Saccharomyces cerevisiae antibody titers are stable over time in Crohn’s patients and are not inducible in murine models of colitis

Table 1 Baseline characteristics of the study populations tested for anti-Saccharomyces cerevisiae IgG and IgA antibodies. Unless otherwise indicated values are numbers of patients (%)

Study population	Crohn’s disease (n = 66)	Ulcerative colitis (n = 29)	Healthy controls (n = 18)	IBS patients (n = 10)
Age, yr
Mean±SD	38±16	37±15	40±13	57±13
Range	14-82	16-78	17-74	41-81
Male sex	32 (48)	15 (52)	10 (56)	6 (60)
Disease location
Colonic	58 (88)	29 (100)
Ileal	45 (68)
Upper gastrointestinal involvement	3 (5)
Presence of fistulae	15 (23)	1 (3)
Extraintestinal manifestations	4 (6)	0 (0)
Medical therapy
Azathioprine	22 (33)	9 (31)
Infliximab	5 (8)	3 (10)
5-ASA compounds	4 (6)	11 (38)
Methotrexate	4 (6)	0 (0)
Oral steroids	29 (44)	15 (52)
None of the above	19 (29)	7 (24)