Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus

Table 6 Multivariate survival analysis for Cox proportional hazards model

Risk factors (# Patients)	Coefficients (SE)	Relative risk (95%CI)	P-values1
t/n TRFLR	0.78 (0.37)	(1.06-4.48)	0.035
≤85% (n = 57)		1
＞85% (n = 17)		2.18
T-status	1.17 (0.78)	(0.70-15.06)	0.134
T1+T2 (n = 13)		1
T3+T4 (n = 61)		3.24
N-status	1.06 (0.66)	(0.79-10.48)	0.108
N0 (n = 24)		1
N1+N2 (n = 50)		2.88
M-status	0.87 (0.43)	(1.03-5.49)	0.042
M0 (n = 60)		1
M1 (n = 14 )		2.38
Stage	-0.90 (0.78)	(0.09-1.89)	0.251
I+II (n = 27)		1
III+IV (n = 47)		0.41
Differentiation	0.33 (0.35)	(0.70-2.76)	0.352
W+M (n = 25)		1
P (n = 49)		1.39
Telomerase expression	-0.11 (0.46)	(0.36-2.22)	0.811
Negative (n = 11)		1
Positive (n = 63)		0.9

¹Wald statistic