Effect of pegylated interferon alpha 2b plus ribavirin treatment on plasma transforming growth factor-&beta;1, metalloproteinase-1, and tissue metalloproteinase inhibitor-1 in patients with chronic hepatitis C

doi:10.3748/wjg.v11.i43.6833

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Nov 21, 2005 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2005; 11(43): 6833-6838
Published online Nov 21, 2005. doi: 10.3748/wjg.v11.i43.6833

Table 3 Correlation expressed by r-value between scored histological picture and TGF-β1, TIMP-1, or MMP-1 in chronic hepatitis C patients before treatmen

	Inflammation		Fibrosis
	Portal	Lobular
TGF-β1 (ng/mL)	0.088	–0.132	0.495^a
TIMP-1 (ng/mL)	0.091	0.326	0.404^a
MMP-1 (ng/mL)	0.229	0.36	–0.018

^aP<0.05 histological score vs TGF-β₁, TIMP-1, and MMP-1

Citation: Flisiak R, Jaroszewicz J, Łapiński TW, Flisiak I, Prokopowiczi D. Effect of pegylated interferon alpha 2b plus ribavirin treatment on plasma transforming growth factor-β1, metalloproteinase-1, and tissue metalloproteinase inhibitor-1 in patients with chronic hepatitis C. World J Gastroenterol 2005; 11(43): 6833-6838
URL: https://www.wjgnet.com/1007-9327/full/v11/i43/6833.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i43.6833