Improvement of regional cerebral blood flow after oral intake of branched-chain amino acids in patients with cirrhosis

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical Research

World J Gastroenterol. Nov 21, 2005; 11(43): 6792-6799
Published online Nov 21, 2005. doi: 10.3748/wjg.v11.i43.6792

Table 1 Patients’ clinical characteristics

Age (yr)	63 ± 8	(48 - 74)
Sex ratio, M/F	30/13
Etiology of cirrhosis, HBV/HCV/unknown	5/32/6
Previous history of overt hepatic encephalopathy,
None/Chronic	Apr-39
Child-Pugh score	8.0 ± 2.2	(5 -13)
Laboratory examinations
Platelet (10⁴µL)	7.5 ± 5.1	(8 - 31.4)
Albumin (g/dL)	2.9 ± 0.5	(1.9 - 3.9)
Total bilirubin (mg/dL)	2.0 ± 2.3	(0.5 - 13.8)
Cholinesterase (∆pH)	0.36 ± 0.19	(0.11 - 0.97)
Plasma ammonia (µmol/L)	38 ± 23	(4 - 104)
Prothrombin time (%)	69.1 ± 12.8	(31.3 - 93.5)
BCAA to tyrosine ratio	3.3 ± 1.3	(1.32 - 6.95)
Neuropsychological test
Trail making test (s)	54 ± 26	(28 - 160)
Digit symbol test (gross point)	35 ± 10	(12 - 54)

BCAA, branched-chain amino acids.

Citation: Yamamoto M, Iwasa M, Matsumura K, Nakagawa Y, Fujita N, Kobayashi Y, Kaito M, Takeda K, Adachi Y. Improvement of regional cerebral blood flow after oral intake of branched-chain amino acids in patients with cirrhosis. World J Gastroenterol 2005; 11(43): 6792-6799
URL: https://www.wjgnet.com/1007-9327/full/v11/i43/6792.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i43.6792

Yamamoto M, Iwasa M, Matsumura K, Nakagawa Y, Fujita N, Kobayashi Y, Kaito M, Takeda K, Adachi Y. Improvement of regional cerebral blood flow after oral intake of branched-chain amino acids in patients with cirrhosis. World J Gastroenterol 2005; 11(43): 6792-6799 [PMID: 16425386 DOI: 10.3748/wjg.v11.i43.6792]

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