Preoperative sorting of circulating T lymphocytes in patients with esophageal squamous cell carcinoma: Its prognostic significance

Table 3 Relationship between serum CD4/CD8 ratio and clinico-pathological features (mean±SD), n (%)

	Group H-CD4/8	Group L-CD4/8	P
Variables	(n = 48)	(n = 86)
Gender
Male	38 (79.2)	80 (93.0)	0.036
Female	10 (20.8)	6 (7.0)
Age	61.4+8.9	63.0+9.6	0.322
Location of tumor
Upper	10 (20.8)	13 (15.1)	0.675
Middle	26 (54.2)	52 (60.5)
Lower	12 (25.0)	21 (24.4)
Degree of differentiation
Well	5 (10.4)	5 (5.8)	0.459
Moderately	36 (75.0)	72 (83.7)
Poorly	7 (14.6)	9 (10.5)
Tumor size (cm)	4.9+2.5	5.6+2.7	0.125
Depth of tumor
Tis	2 (4.2)	2 (2.3)	0.213
T1a	4 (8.3)	7 (8.1)
T1b	11 (22.9)	13 (15.1)
T2	8 (16.7)	15 (17.5)
T3	11 (22.9)	37 (43.0)
T4	12 (25.0)	12 (14.0)
Lymph nodes metastasis
Positive	16 (33.3)	39 (34.9)	0.241
Negative	32 (66.7)	47 (65.1)
Lymphatic invasion
Positive	12 (25.0)	18 (20.9)	0.745
Negative	36 (75.0)	68 (79.1)
Venous invasion
Positive	5 (10.4)	11 (12.8)	0.647
Negative	43 (89.6)	75 (87.2)
TNM stage
0	2 (4.2)	2 (2.3)	0.858
I	13 (27.1)	15 (17.5)
IIA	11 (22.9)	23 (26.7)
IIB	6 (12.5)	12 (14.0)
III	16 (33.3)	34 (39.5)
Curability
Curative resection	36 (75.0)	72 (83.7)	0.830
Non curative resection	12 (25.0)	14 (16.3)

Well = well differentiated squamous cell carcinoma; Moderately = moderately differentiated squamous cell carcinoma; Poorly = poorly differentiated squamous cell carcinoma.