Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression

Table 1 Clinical features of study groups

Variables	HCC (n = 33)	CLD (n = 20)	ASC (n = 20)	NC (n = 20)	P
Age (mean±SD)	55.3±10.1	63.3±8.3	34±7.7	31.7±11.8
Gender (M/F)	27/6	14/6	14/6	12/8
Liver state:
Cirrhosis	30 (91%)	14 (70%)	0	0	0.05
Irregular surface	30 (91%)	12 (60%)	0	0	0.007
Ascites	13 (39.4%)	11 (55%)	0	0	0.27
Jaundice	27 (81.8%)	8 (40%)	0	0	0.002
LL edema1	19 (57.6%)	11 (55%)	0	0	0.85
Megaly	33 (100%)	19 (95%)	0	0	0.38
Spleenomegaly	19 (57.6%)	13 (65%)	0	0	0.59
Schistosomal-Ab	18 (54.5%)	13 (65%)	14 (70%)	1 (5%)	0.45
HCV-Ab	31 (93.9%)	15 (75%)	20 (100%)	1 (5%)	0.05
HBsAg	3 (9%)	6 (30%)	4 (20%)	0	0.05
HCV-RNA	22 (66.7%)	14 (70%)	20 (100%)	0	0.8
Liver function tests
ALT (mean±SD)	67.2±43.3	48±33.1	27.2±(7.0)	25.3±(4.2)	0.06
AST (mean±SD)	126.4±57.4	83.6±54.1	26.1±(5.0)	19.1±(5.0)	0.006
Alk ph (mean±SD)	260.4±193.4	221±126.7	70±26.1	65±24.2	0.414
Bil (mean±SD)	2.28±2.1	2.02±1.9	1.0±0.2	0.9±0.1	0.34

¹LL edema: lower limb edema. P<0.05 difference is statistically significant.