Basic Research
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 7, 2005; 11(41): 6450-6458
Published online Nov 7, 2005. doi: 10.3748/wjg.v11.i41.6450
Table 3 Effect of GSE with or without pretreatment with NG-nitro-L-arginine (L-NNA 20 mg/kg ip) applied with or without the combination with L-arginine (L-Arg, 200 mg/kg ig) or D-arginine (D-Arg, 200 mg/kg ig) on the area of ethanol-induced gastric lesions and accompanying changes in the GBF. Results are mean±SE of 6–8 rats
Type of testMean lesion area (mm2)GBF (% control)
Without L-NNA
Vehicle82 ± 563 ± 3
GSE (32 mg/kg i.g.)8 ± 1.5a81 ± 4a
With L-NNA
Vehicle88 ± 458 ± 3
GSE (32 mg/kg i.g.)76±3c66 ± 5c
L-Arg (200 mg/kg i.g.)
+GSE (32 mg/kg i.g.)12 ± 2c79 ± 3c
D-Arg (200 mg/kg i.g.)
+GSE (32 mg/kg i.g.)72 ± 469 ± 3