Classifying genotype F of hepatitis B virus into F1 and F2 subtypes

Table 4 Homology in the entire nucleotide sequence of the seven HBV/F2 isolates to HBV/F1 isolates and among themselves

	F2 subtype (this study)				F2 subtype (reported)			F1 subtype (this study)
	USF10	USF1122	USF1778	USF2065	1853Nic	2928Nic	LAS2523	USF2573	JPF1130	JPNTAKA	PANAM5	PANAM6	VENEZ2	VENEZ4
HBV/F1 isolates
(reported)
AB036905	91.7	91.9	92.3	92.6	92.3	92.7	92.5	94.6	94.1	93.6	99.2	97.9	99	94.7
AB036910	91.7	91.9	92.3	92.7	92.2	92.6	92.6	94.7	94.1	93.6	99.2	98	99.5	94.8
AB036920	91.7	91.9	92.2	92.5	92.2	92.7	92.5	94.6	94	93.6	99.1	97.8	98.8	94.7
X69798	91.1	91.4	91.9	92.2	91.6	92.1	92.2	94.3	93.9	93.6	96.2	95.2	96.1	94.5
X75659	90.5	90.7	91.2	91.6	91	91.4	91.4	93.6	92.9	92.6	95.4	94.3	95.5	93.7
X75663	91	91.2	91.8	92.2	91.7	92.1	91.9	94	93.3	92.8	97.2	96	97.6	94.1
AY090455	91	91.1	91.5	91.9	91.4	91.9	91.9	94.2	93.8	93.4	96	94.9	95.8	94.3
AY090458	90.8	90.9	91.5	92	91.6	91.9	91.6	97.9	97.3	96.9	94.9	93.8	94.9	98.1
AY090459	90.8	90.8	91.5	91.9	91.6	91.9	91.5	98.2	97.5	97.2	95	93.9	94.9	98.3
AY090461	90.9	91	91.6	92	91.6	91.9	91.7	98.1	97.5	97.1	95	93.9	94.8	98.3
HBV/F1 isolates
(this study)
USF2573	91	91.1	91.6	92	91.8	92.1	91.8	–	98.5	97.9	94.8	93.7	94.7	99.6
JPF1130	90.7	90.6	91.3	91.5	91.3	91.6	91.3	98.5	–	97.8	94.3	93.4	94.2	98.4
JPNTAKA	90.5	90.5	91.1	91.3	91.0	91.3	91.1	97.9	97.8	–	93.9	92.9	93.7	97.9
PANAM5	91.9	92	92.4	92.8	92.3	92.8	92.7	94.8	94.3	93.9	–	98.6	99.2	95
PANAM6	91.1	91.2	91.7	91.7	91.4	91.9	91.7	93.7	93.4	92.9	98.6	–	98	93.8
VENEZ2	91.8	92.1	92.5	92.8	92.3	92.8	92.7	94.7	94.2	93.7	99.2	98	–	94.9
VENEZ4	91.1	91.2	91.7	92.1	91.9	92.2	92	99.6	98.4	97.9	95	93.8	94.9	–
F2 isolates
(this study)
USF10	–	97	96.9	97.2	96.3	96.6	97.9	91.0	90.7	90.5	91.9	91.1	91.8	91.1
USF1122	97	–	97.1	97.6	96.5	96.9	98.2	91.1	90.7	90.5	92	91.2	92.1	91.2
USF1778	96.9	97.1	–	98.6	97.2	97.4	98	91.6	91.3	91.1	92.4	91.7	92.5	91.7
USF2065	97.2	97.6	98.6	–	97.6	97.8	98.4	92	91.5	91.3	92.8	91.7	92.8	92.1
F2 isolates
(reported)
1853Nic	96.3	96.5	97.2	97.6	–	99.2	97.5	91.8	91.3	91.0	92.3	91.4	92.3	91.9
2928Nic	96.6	96.9	97.4	97.8	99.2	–	97.7	92.1	91.6	91.3	92.8	91.9	92.8	92.2
LAS2523	97.9	98.2	98	98.4	97.5	97.7	–	91.8	91.3	91.1	92.7	91.7	92.7	92

Values less than 92, clearing genotype difference, are shown in boldface.