Impact of parietal cell autoantibodies and non-organ-specific autoantibodies on the treatment outcome of patients with hepatitis C virus infection: A pilot study

Table 8 Impact of ANA and SMA alterations at the three time-points of investigation on the sustained combined biochemical and virological response of the patients.

	Combined sustained response at the end of follow up [n (%)]
	n	Yes	No	P
Alteration of ANA titers
Increase	20	7 (35)	13 (35)	0.02
Decrease	13	8 (61.5)	5 (38.5)
Constant	24	4 (16.7)	20 (83.3)
Alteration of SMA titers
Increase	14	2 (14.3)	12 (85.7)	0.001
Decrease	18	12 (66.7)	6 (33.3)
Constant	25	5 (20)	20 (80)

Abbreviations are same as in the text. n = the number of individuals in each group of patients. Alterations of autoantibodies titres are referred to the period from entry to end of follow up. P values were calculated by total χ².