Usefulness of serum des-γ-carboxy prothrombin in detection of hepatocellular carcinoma

Table 2 Diagnostic values of DCP and AFP for the detection of HCC

Groups	Case number	DCP			AFP			DCP/AFP
		40 mAU/mL			20 ng/mL			DCP 40 mAU/mL or AFP 20 ng/mL
		Positive		Negative	Positive		Negative	Positive		Negative
Nonmalignant liver disease
Chronic hepatitis	32	2		30	6		26	8		24
Cirrhosis	34	7		27	9		25	13		21
HCC	61	47		14	36		25	51		10
Overall accuracy (%)			81.9			68.5			75.6
Sensitivity			77.0			59.0			83.6
Specificity			86.4			77.3			68.2
Positive prediction rate			83.9			70.6			70.8
Negative prediction rate			80.3			67.1			81.8

DCP: des-γ-carboxy prothrombin; AFP: α-fetoprotein; HCC: hepatocellular carcinoma