Hepatocellular carcinoma in Egypt: A single center study over a decade

Table 3 Comparison of the main risk factors and pattern of HCC between period I and II of the study among CLD patients attending CLC

	1993-1997		1998-2002		P
	HCC (n = 578)		HCC (n = 750)
	n	%	n	%
Age (yr)					0.387
<40	36	6.2	43	5.7
40-59	362	62.6	497	66.3
60+	180	31.1	210	28
Sex					0.009
Male	477	82.5	657	87.6
Female	101	17.5	93	12.4
Residence					0.411
Rural	475	82.2	603	80.4
Urban	103	17.8	147	19.6
Schistosomiasis	371	64.2	448	59.7	0.098
Blood transfusion	113	19.6	93	12.4	0.00
HCV-Ab	495	85.6	659	87.9	0.233
HBsAg	223	38.6	154	20.5	0.00
Co-infection (HBV+HCV)	156	27	81	10.8	0.00
Non B Non C	16	2.8	18	2.4	0.673
α-Fetoprotein (≥200 ng/mL)	90	15.6	217	28.9	0.00
Number of lesions					0.006
Unifocal	264	45.7	286	38.1
Multifocal	314	54.3	464	61.9
Site of lesion
Right lobe	339	58.7	524	69.9	0.00
Left lobe	73	12.6	105	14
Both	166	28.7	121	16.1
Size of lesion				0.00
1≤3.0 cm	86	14.9	170	22.7
>3.0 cm	492	85.1	580	77.3
PVT2	104	18	134	17.9	0.953

¹May be eligible for intervention!

²PVT; portal vein thrombosis.