MUC1 and MUC5AC mucin expression in liver fluke-associated intrahepatic cholangiocarcinoma

Table 2 Expression of MUC1 and MUC5AC apomucins, demographic data, cancer histopathology, and clinical staging of ICC patients

	Variables	n (87)	%
Age (yr)	≤56	42	48.3
	>56	45	51.7
Sex	Male	59	67.8
	Female	28	32.2
Tumor staging	I–III	14	16.1
	IVA	16	18.4
	IVB	57	65.5
Histological grading	Papillary	20	22.9
	Well-differentiated	26	29.8
	Moderately differentiated	11	12.6
	Poorly differentiated	20	22.9
	Unclassified	10	11.5
Tumor size	≤5 cm	24	27.6
	>5 cm	63	72.4
Vascular invasion	No	30	34.5
	Yes	57	65.5
Neural invasion	No	46	52.9
	Yes	41	47.1
Lymphatic invasion	No	23	26.4
	Yes	64	73.6
Mucin expression	MUC1 and MUC5AC	52	59.7
	MUC1 only	15	17.3
	MUC5AC only	12	13.8
	None	8	9.2
MUC1 expression	Low (0, 1+)	53	60.9
	High (2+, 3+)	34	39.1
MUC5AC expression	Low (0, 1+)	41	47.1
	High (2+, 3+)	46	52.8