Mutation of DNA polymerase β in esophageal carcinoma of different regions

Table 3 Gene and amino acid variations in polβ

Mutation code	Gene variation	Amino acid variation	Mutation
1	375 nt A→G	88 nt Ile→Val
2	454 nt T→C	114 nt Phe→Ser
3	462 nt G→T	117 nt Glu→termination	Termination
		codon	mutation
4	466 nt G→A	118 nt Gly→Glu
5	613 nt A→T	167 nt Lys→Ile
6	648 nt G→C	179 nt Gly→Arg
7	660 nt A→G	183 nt Arg→Gly
8	665 nt T→C	184 nt Gly→Gly	Synonymous
			mutation
9	670 nt A→G	186 nt Glu→Gly
10	737 nt A→T	208 nt Pro→Pro	Synonymous
			mutation
11	740 nt A→G	209 nt Lys→Lys	Synonymous
			mutation
12	177–234 nt deletion		Frameshift
			mutation
			Termination
			mutation