Efficiency and safety of lamivudine therapy in patients with chronic HBV infection, dialysis or after kidney transplantation

doi:10.3748/wjg.v11.i3.400

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2005; 11(3): 400-402
Published online Jan 21, 2005. doi: 10.3748/wjg.v11.i3.400

Table 1 Effectiveness of lamivudine treatment and frequency of YMDD mutant occurrence after lamivudine treatment in chronic hepatitis B patients: with proper renal function, undergoing dialysis and after kidney transplantation.

Patients	n	Elimination of HBV-DNA (%)	Elimination of HBeAg (%)	Appearance of YMDD (%)	Normalization of ALT activity (%)
Normal liver function	68	36 (53)	35 (51)	9¹² (13)	53 (79)
Dialysis	16	9 (56)	6 (38)	0 (0)	15 (94)
After kidney transplantation	7	1 (14)	3 (43)	2 (29)	7 (100)

¹P<0.02, χ² test with Yates’s correction,

²P<0.006, χ² test with Yates’s correction.

Citation: Lapinski TW, Flisiak R, Jaroszewicz J, Michalewicz M, Kowalczuk O. Efficiency and safety of lamivudine therapy in patients with chronic HBV infection, dialysis or after kidney transplantation. World J Gastroenterol 2005; 11(3): 400-402
URL: https://www.wjgnet.com/1007-9327/full/v11/i3/400.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i3.400