Effect of lipopolysaccharide on diarrhea and gastrointestinal transit in mice: Roles of nitric oxide and prostaglandin E2

Table 3 Effects of L-NAME and indomethacin on lipopolysaccharide (LPS)-induced change of small intestinal content (mean±SE).

Treatment	Intestinal content (g/mouse)	% Intestinal content
Saline	0.14±0.02	100
LPS 5 mg/kg	0.18±0.02	129
LPS 10 mg/kg	0.21±0.01a	150
LPS 20 mg/kg	0.25±0.03a	179
LPS 30 mg/kg	0.26±0.03a	185
LPS 20 mg/kg+L-NAME 15 mg/kg	0.16±0.03c	114
LPS 20 mg/kg+indomethacin 15 mg/kg	0.160.02c	114

^aP<0.05 vs the values of normal saline-treated mice,

^cP<0.05 vs the values of LPS alone-treated mice.