Mechanisms of action of leptin in preventing gastric ulcer

Figure 2 A: The ulcer indices of saline and different concentrations of leptin (1-50 μg/kg) against Indo. Each value is a mean±SE. Asterisks indicate significant difference when compared to saline control (^aP < 0.05, ^bP < 0.01); B: The degree of prevention of Indo-induced ulcerations after treatment with different doses of lansoprazole and omeprazole (each used at 1-10 mg/kg), leptin (10 μg/kg) and ranitidine (50 mg/kg). Each value is a mean±SE. Asterisks indicate significant difference (^dP < 0.001) when compared to saline control.