Clinical Research
Copyright ©The Author(s) 2005.
World J Gastroenterol. Jul 21, 2005; 11(27): 4210-4214
Published online Jul 21, 2005. doi: 10.3748/wjg.v11.i27.4210
Table 2 Changes of acid reflux variables and DeMeester score in 26 patients with GERD after treatment with 150 or 300 mg of itopride
VariableGroup (mg/d)Itopride Tx.nMeanSDP
Number of acid refluxes150Pre1299.2588.570.97
Post1276.9260.53
300Pre13150.77246.150.057
Post1352.2339.79
Number of acid refluxes longer than 5 min150Pre126.085.320.287
Post123.835.32
300Pre136.235.120.054
Post132.692.5
Longest time acid refluxes (min)150Pre1230.5533.370.018
Post1214.0911.03
300Pre1330.2556.40.289
Post1320.7833.64
Total time below pH 4 (min)150Pre12138.4298.560.16
Post1292.0978.07
300Pre13145.0886.10.011
Post1371.7751.43
Fraction time below pH 4 (%)150Pre1211.139.260.211
Post1210.1212.69
300Pre1311.26.690.005
Post135.273.57
DeMeester score150Pre1232.516.960.16
Post1222.8918.75
300Pre1344.4837.50.007
Post1319.5614.72