Microsatellite instable double primary cancers of the colorectum and stomach exhibit less favorable outcome

Table 2 Microsatellite instability (MSI) and follow-up results of double primary gastric and colorectal cancers

Case	Gastric cancer (GC)						Colorectal cancer (CRC)						Follow-up (mo)
	bat26	D5S346	bat25	D17S250	D2S123	MSI	bat26	D5S346	bat25	D17S250	D2S123	MSI
1	●	●			●	H	●		●	⊙		H	21, alive, RGC
													22, alive, RCRC
2	●	●	●	⊙	●	H	●	●	⊙	⊙	⊙	H	88, alive, MGC, kidney
3	●	●	●	⊙	●	H	●	○	●	○	●	H	58, alive, +AOV cancer
4	●	○	●	○	○	H	●	○	●	○	○	H	10, alive, RCRC
5	●	●	●	●	●	H	●	○	⊙	⊙	⊙	I	18, alive, NED
6	○	○	●	○	○	L	⊙	⊙	⊙	⊙	⊙	I	38, alive, NED
7	○	○	○	○	○	S	○	○	○	○	○	S	29, alive, NED
8	○	○	○	○	○	S	○	○	○	○	○	S	18, alive, NED
9	○	○	○	○	○	S	○	○	○	○	○	S	114, alive, NED
10	○	○	○	○	○	S	○	○	○	○	○	S	85, alive, NED
11	○	○	○	○	○	S	○	○	○	○	○	S	61, alive, NED
12	○	○	○	○	○	S	○	○	○	○	○	S	82, alive, NED
13	⊙	⊙	⊙	⊙	⊙	I	○	○	○	○	○	S	19, alive, NED
14	○	○	○	○	○	S	⊙	⊙	⊙	⊙	⊙	I	17, alive, NED
15	⊙	○	⊙	⊙	⊙	I	○	○	○	○	○	S	29, alive, NED
16	⊙	○	⊙	⊙	⊙	I	○	○	○	○	○	S	67, alive, MCRC, lung

H, MSI-high; L, MSI-low; I, inconclusive; NED, no evidence of disease; RGC, recurrent gastric cancer; RCRC, recurrent colorectal cancer; MGC, metastatic gastric cancer; MCRC, metastatic colorectal cancer; AOV, ampulla of Vater.