Impact of simultaneous assay, the PCNA, cyclinD1, and DNA content with specimens before and after preoperative radiotherapy on prognosis of esophageal cancer-possible incorporation into clinical TNM staging system

Table 2 Independent predictors of survival in 47 esophageal SCC patients according to multivariate Cox regression analysis

Factors	Group	Group value	β value	SD	P	Risk
Pathological radiation change’s	III/II/I Grades	0/1/2	0.6405	0.2451	0.0090	0.1582
Surgical specimens T stage	T1/T2/T3	0/1/2	0.7678	0.2737	0.0050	0.1744
Surgical specimens N stage	N0/N1	0/1	1.2957	0.4845	0.0075	0.1634
Pre-radiotherapy cyclinD	N/P/SP	0/1/2	0.8434	0.2564	0.0010	0.2139
Post-radiotherapy cyclinD1	N/P/SP	0/1/2	0.6538	0.2643	0.0134	0.1462
Post-radiotherapy PCNA	Low/high expression	0/1	2.0965	0.4720	0.0000	0.3032
Post-radiotherapy DNA	I+II Type/III+IV Type	0/1	1.5593	0.4287	0.0003	0.2413