Depletion of CD25+CD4+T cells (Tregs) enhances the HBV-specific CD8+ T cell response primed by DNA immunization

Figure 1 Injection of anti-CD25 mAb results in selective loss of CD25⁺ cells. Mice (six mice per group) were injected with 500 μg of anti-CD25 mAb (PC61) and analyzed by flow cytometry at the indicated days after treatment. Representative responses of PBMCs from one mouse are shown (A). Data are expressed as a percentage of CD25⁺CD4⁺ cells in the CD4⁺ cell population in peripheral blood. Three experiments were performed with similar results (B). Data are shown as the mean±SD of six mice tested individually n = 6.