High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis

Figure 2 Light microscopic distributions of immunohistochemically stained CAV-1 and -2 in PBC stage 1 liver tissue. A: CAV-1, ×100; B: CAV-2, ×100; C: double staining of CAV-1 and cytokeratin 7, ×100; D: double staining of CAV-2 and cytokeratin 7, ×100. Hematoxylin counterstain. Immunostaining of CAV-1 and -2 is observed to some degree on interlobular bile ducts, intense immunostaining on proliferative bile ductules, and some immunostaining on hepatic sinusoidal lining cells. Asterisks denote interlobular bile ducts.