Gastric Cancer
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Jun 7, 2005; 11(21): 3175-3181
Published online Jun 7, 2005. doi: 10.3748/wjg.v11.i21.3175
Table 4 Distribution of genetic polymorphisms of the GSTM1, GSTT1, CYP1A1, CYP2E1, and ALDH2 genes in cases and controls.
GenotypeNumber (%)
Total (%)OR1 (95%CI2)
CasesControls
CYP1A1
Ile/Ile246 (58.9)415 (65.8)661 (63.0)1.00
Ile/Val or Val/Val172 (41.1)216 (34.2)388 (37.0)1.34a (1.04, 1.73)
CYP2E1
c1/c1268 (64.4)400 (63.5)668 (63.9)1.00
c1/c2 or c2/c2148 (35.6)230 (36.5)378 (36.1)0.96 (0.74, 1.24)
GSTT1
Non-null229 (57.3)367 (59.8)596 (58.8)1.00
Null171 (42.7)247 (40.2)418 (41.2)1.11 (0.86, 1.44)
GSTM1
Non-null149 (37.3)254 (41.4)403 (39.7)1.00
Null251 (62.7)360 (58.6)611 (60.3)1.18 (0.91, 1.53)
ALDH2
*1/*1286 (67.9)462 (73.3)748 (71.2)1.00
*1/*2 or *2/*2135 (32.1)168 (26.7)303 (28.8)1.30 (0.99, 1.70)