MELD vs Child-Pugh and creatinine-modified Child-Pugh score for predicting survival in patients with decompensated cirrhosis

Table 3 Association of baseline characteristics with survival in 102 patients with decompensated cirrhosis (results from univariate Cox proportional hazards models).

Patient characteristic	Hazard ratio	95%CI	P
Age (per yr)	0.99	0.90-1.03	0.72
Sex (male)	0.68	0.27-1.72	0.92
Cause of cirrhosis (unknown)
HBV	0.41	0.12-1.58	0.21
HCV	1.21	0.35-4.17	0.77
Alcohol	0.72	0.27-1.93	0.51
PBC/PSC	0.97	0.47-3.85	0.68
SBP on admission	4.25	1.41-12.84	0.01
White blood count (×109/L)	1.12	0.43-3.68	0.90
Platelet count (×109/L)	1.06	0.52-2.15	0.87
Prothrombin time (s)	2.48	0.50-12.19	0.26
INR	4.22	0.98-18.19	0.052
Creatinine (mg/dL)	4.62	1.76-12.13	0.012
Bilirubin (mg/dL)	2.25	1.5-3.38	<0.001
AST (IU/L)	1.95	1.12-3.4	0.018
ALT (IU/L)	1.70	1.03-2.8	0.039
Alkaline phosphatase (U/L)	0.83	0.38-1.86	0.66
GGT (U/L)	1.64	1.09-2.46	0.019
Albumin (g/dL)	0.53	0.07-3.84	0.53
Child class (A)
B	2.11	0.46-9.77	0.34
C	3.71	0.78-17.61	0.1

CI: confidence interval, HBV: hepatitis B virus, HCV: hepatitis C virus, PBC: primary biliary cirrhosis, PSC: primary sclerosing cholangitis, SBP: spontaneous bacterial peritonitis, INR: international normalized ratio, AST: aspartate aminotransferase, ALT: alanine aminotransferase, GGT: gamma-glutamyl-transpeptidase, MELD: Model for End-stage Liver Disease. Hazard ratios (95%CI) for quantitative variables are expressed for 1 relevant unit increase of loge.