Hypermethylation of CpG island in O6-methylguanine-DNA methyltransferase gene was associated with K-ras G to A mutation in colorectal tumor

doi:10.3748/wjg.v11.i13.2022

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Apr 7, 2005 (publication date) through Apr 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2005; 11(13): 2022-2025
Published online Apr 7, 2005. doi: 10.3748/wjg.v11.i13.2022

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Figure 1 Methylation-specific PCR result of MGMT in colorectal tumors and normal colorectal mucosa. Colorectal carcinomas (45 °C) showed both unmethylated (U) and methylated (M) bands, but normal tissues (N) showed only unmethylated bands.

Citation: Qi J, Zhu YQ, Huang MF, Yang D. Hypermethylation of CpG island in O⁶-methylguanine-DNA methyltransferase gene was associated with K-ras G to A mutation in colorectal tumor. World J Gastroenterol 2005; 11(13): 2022-2025
URL: https://www.wjgnet.com/1007-9327/full/v11/i13/2022.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i13.2022