Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn&rsquo;s disease: Phenotype-genotype correlations

doi:10.3748/wjg.v11.i10.1489

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Mar 14, 2005; 11(10): 1489-1495
Published online Mar 14, 2005. doi: 10.3748/wjg.v11.i10.1489

Table 4 NOD2/CARD15 SNP8, 12 and 13 in patients with Crohn’s disease (CD) and controls.

	R702W (SNP8)¹		G908R(SNP12)		3020insC (SNP13)¹
	CD n (%)	Controls n (%)	CD n (%)	Controls n (%)	CD n (%)	Controls n (%)
Wild type	466 (88.4)	188 (94.0)	494 (96.7)	193 (96.5)	425 (80.6)	190 (95.0)
All carriers	61 (11.6)	12 (6.0)	33 (6.3)	7 (3.5)	102 (19.4)	10 (5.0)
Heterozygous	45 (8.5)	12 (6.0)	33 (6.3)	7 (3.5)	89 (16.9)	10 (5.0)
Homozygous	16 (3.1)	0	0	0	13 (2.5)	0

¹P = 0.02 and P<0.0001 between patients and controls for genotype frequency by χ²-test, OR_{SNP8 allele} = 2.41 (1.30–4.44), OR_{SNP13 allele} = 4.78 (2.50–9.11).

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Citation: Lakatos PL, Lakatos L, Szalay F, Willheim-Polli C, Österreicher C, Tulassay Z, Molnar T, Reinisch W, Papp J, Mozsik G, Group HIS, Ferenci P. Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn’s disease: Phenotype-genotype correlations. World J Gastroenterol 2005; 11(10): 1489-1495
URL: https://www.wjgnet.com/1007-9327/full/v11/i10/1489.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i10.1489

Lakatos PL, Lakatos L, Szalay F, Willheim-Polli C, Österreicher C, Tulassay Z, Molnar T, Reinisch W, Papp J, Mozsik G, Group HIS, Ferenci P. Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn’s disease: Phenotype-genotype correlations. World J Gastroenterol 2005; 11(10): 1489-1495 [PMID: 15770725 DOI: 10.3748/wjg.v11.i10.1489]

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