Identify lymphatic metastasis-associated genes in mouse hepatocarcinoma cell lines using gene chip

Table 1 Differential gene expression profile in cell lines Hca-F vs Hca-P.

Gene	Symbol descriptions	F vs P_Signal log ratio
Slc38a4	Solute carrier family 38, member 4
	1gb: NM_027052	9
	gb: AK003626	3.4
Krt2-8	Keratin complex 2, basic, gene 8
	gb: M21836	8.6
	gb: NM_031170	4.8
Krt1-19	Keratin complex 1, acidic, gene 19	7.4
Cldn9	Claudin 9	7.4
Gja1	Gap junction membrane channel protein alpha 1
	gb: M63801	7.2
	gb: BC006894	6.4
Fbp2	Fructose bisphosphatase 2	7.1
R75183	Expressed sequence R75183
	gb: BC004774	7
	gb: BB324973	5.5
Egfr	Epidermal growth factor receptor
	gb: AF275367	6.9
	gb: U03425	3.6
Lepr	Leptin receptor	6.7
Tm4sf3	Transmembrane 4 superfamily member 3	6.5
Pla2g1b	Phospholipase A2, group IB, pancreas	6.4
Ripk3	Receptor-interacting serine-threonine kinase 3	6.4
Igfbp4	Insulin-like growth factor binding protein 4
	gb: NM_010517	6.3
	gb: BC019836 21423756_s_at	5.8
	gb: BC019836 1423757_x_at	4.1
	gb: AA119124	4
Piwil2	Piwi-like homolog 2 (Drosophila)	6.3
IL24	Interleukin 24	5.9
Daf1	Decay accelerating factor 1	5.9
Cav	Caveolin, caveolae protein	5.8
Arhgef3	Rho guanine nucleotide
	exchange factor (GEF) 3	5.7
Efna1	Ephrin A1
	gb: D38146	5.7
	gb: BC002046	4.2
Ptpn8	Protein tyrosine phosphatase,
	non-receptor type 8	5.6
Rab3b	RAB3B, member RAS oncogene family	5.6
1190003K14Rik	RIKEN cDNA 1190003K14 gene	5.6
Sh3bp5	SH3-domain binding protein 5
	(BTK-associated)	5.5
Fscn1	Fascin homolog 1, actin bundling protein
	(Strongylocentrotus purpuratus)
	gb: NM_007984 1416514_a_at	5.4
	gb: BE952057	4.2
	gb: NM_007984 1448378_at	3.7
Fgf15	Fibroblast growth factor 15	5.4
Ehox	ES cell derived homeobox containing gene	5.3
Ankrd1	Ankyrin repeat domain 1 (cardiac muscle)
	gb: NM_013468	5.3
	gb: AK009959	3.6
1600023A02Rik	RIKEN cDNA 1600023A02 gene	5.3
Cd109	CD109 antigen	5.3
BC037006	cDNA sequence BC037006	5.3
Ltb4dh	Leukotriene B4 12-hydroxydehydrogenase	5.2
Krt2-7	Keratin complex 2, basic, gene 7	5.2
Cnn2	Calponin 2	5.2
Sema3b	Sema domain, immunoglobulin domain (Ig),
	short basic domain, secreted, (semaphorin) 3B
	gb: BB116052	5.1
	gb: NM_009153	4.7
Krt1-18	Keratin complex 1, acidic, gene 18	5.1
	Mouse gene for 18S rRNA	5.1
Fosl1	Fos-like antigen 1
	gb: NM_010235	5
	gb: U34245	4.4
Sncg	Synuclein, gamma	5
Col8a1	Procollagen, type VIII, alpha 1	4.9
Pcdhb7	Protocadherin beta 7	4.9
Msln	Mesothelin	4.9
IL23a	Interleukin 23, alpha subunit p19	4.9
	Mus musculus adult male tongue cDNA	4.8
Ppp1r14a	Protein phosphatase 1, regulatory
	(inhibitor) subunit 14A	4.7
Csf3	Colony stimulating factor 3 (granulocyte)	4.7
Nfil3	Nuclear factor, interleukin 3, regulated	4.6
Procr	Protein C receptor, endothelial	4.6
Nr1d1	Nuclear receptor subfamily 1,
	group D, member 1	4.6
2810003C17Rik	RIKEN cDNA 2810003C17 gene	4.6
MGC27770	Hypothetical protein MGC27770	4.5
Eng	Endoglin	4.5
F2r	Coagulation factor II (thrombin) receptor	4.5
Cdc42ep5	CDC42 effector protein
	(Rho GTPase binding) 5	4.4
Pla2g7	Phospholipase A2, group VII
	(platelet-activating factor
	acetylhydrolase, plasma)	4.4
D18Ertd653e	DNA segment, Chr 18,
	ERATO Doi 653, expressed	4.4
IL2rg	Interleukin 2 receptor, gamma chain
	gb: L20048 1416296_at	4.3
	gb: L20048 1416295_a_at	3.3
Smpd2	Sphingomyelin phosphodiesterase 2, neutral	4.3
Areg	Amphiregulin	4.3
Mcam	Melanoma cell adhesion molecule	4.2
Rtn2	Reticulon 2 (Z-band associated protein)	4.2
Gcnt2	Glucosaminyltransferase, I-branching enzyme	4.2
D7Ertd458e	DNA segment, Chr 7, ERATO Doi 458, expressed
	gb: NM_009310	4.2
	gb: BB049138 1423904_a_at	4
	gb: BC013673 1451160_s_at	4
	gb: BB049138 1423905_at	3.9
	gb: BC013673 1423903_at	3.8
Chi3l3	Chitinase 3-like 3	4.1
D4Ertd765e	DNA segment, Chr 4,
	ERATO Doi 765, expressed	4.1
Ptpr	Protein tyrosine phosphatase, receptor type, R	4.1
Scn8a	Sodium channel, voltage-gated, type VIII,
	alpha polypeptide	4
AXL	AXL receptor tyrosine kinase	4
Serpinh1	Serine (or cysteine) proteinase inhibitor,
	clade H, member 1	4
Panx1	Pannexin 1	3.9
Tm4sf9	Transmembrane 4 superfamily member 9	3.9
Mak	Male germ cell-associated kinase	3.9
	Mus musculus transcribed sequences	3.8
9130017N09Rik	RIKEN cDNA 9130017N09 gene	3.8
Loxl2	Lysyl oxidase-like 2	3.7
Dok1	Downstream of tyrosine kinase 1	3.6
Abhd3	Abhydrolase domain containing 3	3.6
Ramp3	Receptor (calcitonin) activity
	modifying protein 3	3.6
Fibp	Fibroblast growth factor (acidic)
	intracellular binding protein	3.6
Wscr5	Williams-Beuren syndrome chromosome
	region 5 homolog (human)	3.6
Eppk1	Epiplakin 1	3.6
2010004A03Rik	RIKEN cDNA 2010004A03 gene	3.6
Itgb5	Integrin beta 5
	gb: NM_010580 1417534_at	3.5
	gb: NM_010580 1417533_a_at	3.3
Mlf1	Myeloid leukemia factor 1	3.5
Tnfrsf22	Tumor necrosis factor receptor
	superfamily, member 22	3.5
Zdhhc2	Zinc finger, DHHC domain containing 2	3.5
Tnfaip2	Tumor necrosis factor, alpha-induced protein 2	3.4
Rrad	Ras-related associated with diabetes	3.4
A530090O15Rik	RIKEN cDNA A530090O15 gene	3.4
Chi3l4	Chitinase 3-like 4	3.4
Tnfrsf19	Tumor necrosis factor receptor
	superfamily, member 19	3.4
Myo1b	Myosin IB
	gb: AI255256	3.4
	gb: BI080370	3.2
Tuba4	Tubulin, alpha 4	3.3
Myo1g	Myosin IG	3.3
Siat10	Sialyltransferase 10
	(alpha-2,3-sialyltransferase VI)	3.3
Nol3	Nucleolar protein 3
	(apoptosis repressor with CARD domain)	3.3
Tpt1h	tRNA splicing 2’ phosphotransferase 1
	homolog (S. cerevisiae)	3.3
Igfbp6	Insulin-like growth factor binding protein 6	3.3
Ccnd1	Cyclin D1
	gb: M64403	3.2
	gb: NM_007631	3.1
BC003236	cDNA sequence BC003236	3.2
2010001C09Rik	RIKEN cDNA 2010001C09 gene	3.2
Chst1	Carbohydrate (keratan sulfate Gal-6)
	sulfotransferase 1	3.2
Timp1	Tissue inhibitor of metalloproteinase 1	3.2
4921530G04Rik	RIKEN cDNA 4921530G04 gene	3.2
Lxn	Latexin	3.1
Sgk2	Serum/glucocorticoid regulated kinase 2	3.1
2310047E01Rik	RIKEN cDNA 2310047E01 gene	3.1
2200002N01Rik	RIKEN cDNA 2200002N01 gene	3
Ptpre	Protein tyrosine phosphatase, receptor type, E	3
Psmb8	Proteosome (prosome, macropain) subunit, beta
	type 8 (large multifunctional protease 7)	3
Tm7sf1	Transmembrane 7 superfamily member 1	3