E-cadherin gene C-160A promoter polymorphism and risk of non-cardia gastric cancer in a Chinese population

Table 3 Stratification analyses of CDH1 genotype frequencies, ORs and 95% CIs in gastric cancer.

Variables	Cases		Controls		OR (95%CI)1
	CC n (%)	CA+AA n (%)	CC n (%)	CA+AA n (%)
Total	119 (57.7)	87 (42.2)	152 (58.2)	109 (41.8)
Age (yr)
≤60	53 (59.6)	36 (40.4)	66 (57.9)	48 (42.1)	0.86 (0.47-1.56)
>60	66 (56.4)	51 (43.6)	86 (58.5)	61 (41.5)	1.20 (0.71-2.00)
Sex
Male	90 (60.0)	60 (40.0)	107 (56.3)	83 (43.7)	0.92 (0.58-1.44)
Female	29 (51.8)	27 (48.2)	45 (63.4)	26 (36.6)	1.81 (0.85-3.86)
Residence
Jin-tan	56 (59.0)	39 (41.0)	80 (55.2)	65 (44.8)	0.90 (0.52-1.57)
Huai-an	63 (56.8)	48 (43.2)	72 (62.1)	44 (37.9)	1.31 (0.76-2.27)
Smoking
No	54 (64.3)	30 (35.7)	58 (58.0)	42 (42.0)	0.79 (0.43-1.48)
Yes	65 (53.3)	57 (46.7)	93 (58.5)	66 (41.5)	1.31 (0.79-2.16)
Alcohol Drinking
No	71 (60.2)	47 (39.8)	88 (64.7)	48 (35.3)	1.27 (0.75-2.15)
Yes	48 (54.6)	40 (45.5)	64 (51.2)	61 (48.8)	0.92 (0.51-1.63)
H pylori infection
Negative	54 (59.3)	37 (40.7)	55 (59.1)	38 (40.9)	0.98 (0.53-1.80)
Positive	65 (56.5)	50 (43.5)	95 (57.3)	71 (36.7)	1.03 (0.63-1.71)
Family history of gastric cancer
No	94 (57.7)	69 (42.3)	138 (58.7)	97 (41.3)	1.07 (0.71-1.62)
Yes	24 (57.1)	18 (42.9)	14 (56.0)	11 (44.0)	1.40 (0.45-4.39)

¹ORs were adjusted for age, sex, smoking, alcohol drinking, residence, tea consumption, H pylori infection and family history of gastric cancer in a logistic regression model.