Mast Cell And Inflammatory Bowel Disease
Copyright ©The Author(s) 2004.
World J Gastroenterol. Feb 1, 2004; 10(3): 319-322
Published online Feb 1, 2004. doi: 10.3748/wjg.v10.i3.319
Table 2 Effects of pertussis toxin and metabolic inhibitors on calcium ionophore induced tryptase and histamine release from colonic mast cells
TreatmentMediator release (ng/mL)
TryptaseHistamine
Untreated13.8 ± 2.434.3 ± 3.4
Pertussis toxin0.1 μg/mL4.0 ± 1.6a2.7 ± 2.8a
1.0 μg/mL1.4 ± 1.8a-0.1 ± 1.3a
Metabolic inhibitors2.0 ± 1.4a1.8 ± 2.6a