Ethanol inhibits the motility of rabbit sphincter of Oddi in vitro

Figure 1 Basal SO motility inhibited by ETOH. Sphincter of Oddi (SO) was exposed to increasing doses of ethanol (ETOH; 2 mL/L, 4 mL/L, 6 mL/L and 8 mL/L). Each concentration of ETOH was administered for 10 min. A: Effect of ETOH on the baseline amplitude. Representative experiments of the control and the ETOH-treated groups are shown. B: Summary of the effect of ETOH on the baseline amplitude. Mean ± SE, n = 5, ^aP < 0.05 vs the control; o: no contractile activity. C: Effect of ETOH on the contractile frequency. Representative experiments of the control and the ETOH-treated groups are shown. D: Summary of the effect of ETOH on the contractile frequency. Mean ± SE, n = 5, ^aP < 0.05 vs the control; o: no contractile activity.