DNA ploidy and c-Kit mutation in gastrointestinal stromal tumors

Table 3 Comparison of clinicopathologic parameters accord-ing to c-Kit mutations

Parameter	Mutations		P
	Negative (n = 20)	Positive (n = 35)
Sex (M:F)	11:9	14:21	0.283
Age (mean, yr)	58.2	61.0	0.360
Mean tumor size (cm)	3.8	6.2	0.020
Mean mitoses counts	7.8	13.4	0.360
Risk group: Very low/low	14	22	0.592
Intermediate/high	6	13
Cellularity: Low	5	6	0.741
Intermediate	13	24
High	2	5
Nuclear atypia Mild	10	17	0.898
Moderate	7	14
Severe	3	4
Necrosis Absent	18	26	0.161
Present	2	9
Hemorrhage Absent	17	21	0.054
Present	3	14
Infiltrative growth Absent	12	18	0.539
Present	8	17
Tumor cell type Spindle	13	27	0.330
Epithelioid	7	8