A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer

Table 4 Interaction between C/T polymorphism and H pylori CagA status for the risk of gastric cancer

C/T polymorphism	CagA antibody	Total cases (n = 143)	Controls (n = 178)	OR1	95%CI	IGC (n = 93)	OR2	95%CI	GCC (n = 50)	OR3	95%CI
CC	No	87	64	1.00		61	1.00		26	1.00
CT + TT	No	28	19	2.53	1.29-4.98	17	2.19	1.01-4.76	11	3.52	1.44–8.61
CC	Yes	21	73	0.45	0.25-0.81	12	0.34	0.17-0.70	9	0.76	0.33-1.73
CT + TT	Yes	7	22	0.43	0.17-1.10	3	0.24	0.07-0.89	4	0.86	0.27-2.79

¹Adjusted for age and gender, χ²_trend = 33.40, df = 1, P = 0.00, γ = -0.84/-0.79 = 1.06 ²Adjusted for age and gender, χ²_trend = 28.53, ^df = 1, P = 0.00, γ = -1.41/-1.08 = 1.31 ³Adjusted for age and gender, χ²_trend = 12.42, ^df = 1, P = 0.0004, γ = -0.15/-0.27 = 0.56.