A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer

Table 3 Interaction between C/T polymorphism and past alcohol drinking for the risk of gastric cancer

C/T polymorphism	Past alcohol drinking	Total cases (n = 143)	Controls (n = 246)	OR1	95%CI	IGC (n = 93)	OR2	95%CI	GCC (n = 50)	OR3	95%CI
CC	No	76	157	1.00		53	1.00		23	1.00
CT + TT	No	24	51	0.83	0.46-1.50	13	0.62	0.30-1.28	11	1.22	0.55-2.70
CC	Yes	32	32	1.34	0.72-2.52	20	1.36	0.67-2.75	12	1.27	0.50-3.19
CT + TT	Yes	11	6	3.33	1.14-9.67	7	3.42	1.03-11.35	4	3.25	0.80-13.13

¹Adjusted for age and gender, χ²_trend = 10.29, ^df = 1, P = 0.001, γ = 1.20/0.30 = 4.00

²Adjusted for age and gender, χ²_trend = 5.65, ^df = 1, P = 0.017, γ = 1.23/0.31 = 3.97

³Adjusted for age and gender, χ²_trend = 8.95, ^df = 1, P = 0.003, γ = 1.18/0.24 = 4.9.