A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer

Table 2 Interaction between C/T polymorphism and past cigarette smoking for the risk of gastric cancer

C/T polymo rphism	Past smoking	Total cases (n = 143)	Controls (n = 246)	OR1	95%CI	IGC (n = 93)	OR2	95%CI	GCC (n = 50)	OR3	95%CI
CC	No	67	162	1.00			46	1.00	21	1.00
CT + TT	No	22	51	0.98	0.55-1.78	12	0.75	0.36-1.54	10	1.44	0.63-3.27
CC	Yes	41	27	2.92	1.53-5.57	27	2.47	1.19-5.09	14	3.65	1.42-9.38
CT + TT	Yes	13	6	3.62	1.23-10.64	8	3.06	0.91-10.35	5	4.63	1.15-18.58

¹Adjusted for age and gender, χ²_trend = 26.26, ^df = 1, P = 0.00, γ = 1.29/1.07 = 1.21

²Adjusted for age and gender, χ²_trend = 18.40, ^df = 1, P = 0.00, γ = 1.12/0.90 = 1.24

³Adjusted for age and gender, χ²_trend = 17.53, ^df = 1, P = 0.00, γ = 1.53/1.29 = 1.19.