Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway

Figure 2 Tumor cell random motility determined by gold-col-loid assay. Cells were seeded onto the coverslips and allowed to adhere for 1 h and then incubated in FBS containing LPA with or without Y-27632 for 24 h. The areas of clearing in the gold colloid corresponding to phagokinetic cell tracks were counted and represented as ^-x±s from triplicate experiments. ^aP < 0.01 LPA treated cells vs SMMC-7721 control cells, ^bP < 0.01 Y-27632 treated cells vs LPA treated cells.