Expression of liver insulin-like growth factor 1 gene and its serum level in rats with diabetes

Table 1 Glucose metabolic parameters during the experiment

Group	Duration (month)	n	Initial weight (g)	Weight (g)	Blood (mmol·L-1)	Aminofructose (mmol·L-1)
NC	0.5	5	198.41 ± 9.76	249.33 ± 16.02	5.14 ± 0.91	0.82 ± 0.07
	2	5	202.53 ± 17.67	351.20 ± 18.23	5.3 ± 0.44	0.85 ± 0.08
	3	6	200.06 ± 13.03	402.05 ± 37.10	4.91 ± 0.26	0.81 ± 0.09
	6	5	199.65 ± 15.22	544.54 ± 30.41	5.21 ± 0.47	0.85 ± 0.05
ID-1	0.5	5	196.25 ± 14.22	254.31 ± 20.97	4.93 ± 0.72	0.79 ± 0.05
	2	4	202.34 ± 19.12	345.75 ± 23.48	5.10 ± 0.62	0.84 ± 0.08
	3	5	196.42 ± 11.41	411.31 ± 47.37	4.88 ± 0.67	0.78 ± 0.06
	6	6	198.68 ± 12.64	538.52 ± 31.62	4.94 ± 0.58	0.84 ± 0.07
ID-2	0.5	5	192.00 ± 5.70	217.00 ± 9.64a	11.4 ± 0.56c	1.02 ± 0.14c
	2	5	199.00 ± 16.73	241.00 ± 16.44c	10.94 ± 1.08c	1.00 ± 0.29c
	3	6	198.66 ± 14.36	256.83 ± 14.98c	10.86 ± 0.94c	0.98 ± 0.08c
	6	5	201.37 ± 14.11	266.24 ± 13.53c	12.13 ± 0.63c	1.10 ± 0.14c
ID-3	0.5	5	208.60 ± 13.08	205.75 ± 15.34b	18.34 ± 1.03ce	1.20 ± 0.12ce
	2	5	198.60 ± 16.66	192.80 ± 13.35cd	17.48 ± 0.62ce	1.18 ± 0.21ce
	3	5	211.50 ± 11.37	204.8 ± 11.03ce	17.50 ± 1.05ce	1.21 ± 0.19ce
	6	6	204.35 ± 12.34	185.22 ± 14.36ce	16.89 ± 0.95ce	1.2 ± 0.34ce

Data expressed as mean ± SD. NC, normal control group; ID-1,-2 ,-3, insulin treatment group. vs NC,

^aP < 0.0025,

^bP < 0.001,

^cP < 0.0001; vs ID-2 (for the same period),

^dP < 0.001,

^eP < 0.0001.