Association of interleukin-12 p40 gene 3&rsquo;-untranslated region polymorphism and outcome of HCV infection

doi:10.3748/wjg.v10.i16.2330

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Aug 15, 2004 (publication date) through May 15, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Aug 15, 2004; 10(16): 2330-2333
Published online Aug 15, 2004. doi: 10.3748/wjg.v10.i16.2330

Table 2 Genotype frequencies of 1188A/C SNP of IL12B in patients

Genotype	Self-limited infection (%)n = 42	Persistent infection (%)n = 91	OR	95%CI	P
AA	8 (19.0)	37 (40.7)	0.34	0.12-0.87	0.014
CC	7 (16.7)	23 (25.3)	0.59	0.20-1.61	0.270
AC	27 (64.3)	31 (34.1)	3.48	1.52-8.10	0.001

Comparisons of genotype distribution using chi square test showed significant difference between self-limited infection and persistent infection (P = 0.004).

Citation: Yin LM, Zhu WF, Wei L, Xu XY, Sun DG, Wang YB, Fan WM, Yu M, Tian XL, Wang QX, Gao Y, Zhuang H. Association of interleukin-12 p40 gene 3’-untranslated region polymorphism and outcome of HCV infection. World J Gastroenterol 2004; 10(16): 2330-2333
URL: https://www.wjgnet.com/1007-9327/full/v10/i16/2330.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i16.2330