Gene expression profiles in an hepatitis B virus transfected hepatoblastoma cell line and differentially regulated gene expression by interferon-α

Table 4 Functional catalogues of 3 fold regulated genes in HepG₂ and HepG₂ 2.2.15 cell lines post IFN-α treatment

Catalogue	3-fold regulated gene number in HepG22.2.15			3-fold regulated gene number in HepG2
	6 h/0 h	24 h/0 h	48 h/0 h	6 h/0 h	24 h/0 h	48 h/0 h
Cell cycle	-	1	1	-	-	-
Coagulation	-	1	1	-	1	-
Cytokine/receptors	1	2	2	1	1	-
Extracellular matrix and cell adhesion	-	-	1	-	1	-
GTP binding proteins and signal transduction	2	-	1	-	1	1
Interferon	8	6	3	6	5	5
Kinase and phosphatase	-	-	1	-	2	-
Ligands and receptors	-	1	2	-	-	-
Mitochondrial	-	1	1	-	2	-
Phosphatase and phosphodiesterase	2	2	2	1	2	1
Protooncogenes	-	1	-	1	-	-
Transcription factors	-	-	-	1	1	1
Viral and clathrin receptors	-	1	1	-	1	-
Miscellaneous	7	8	8	14	18	13
New ESTs	14	24	21	59	68	27
Total	34	48	45	83	103	48