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©The Author(s) 2004.
World J Gastroenterol. May 15, 2004; 10(10): 1431-1435
Published online May 15, 2004. doi: 10.3748/wjg.v10.i10.1431
Published online May 15, 2004. doi: 10.3748/wjg.v10.i10.1431
Table 3 Relationship between clinicopathological features and LOH of 10 loci on long arm of chromosome 1
| D1S498 | D1S484 | D1S218 | D1S238 | D1S413 | D1S249 | D1S213 | D1S2800 | D1S2785 | D1S2836 | ||||||||||||
| N | L | N | L | N | L | N | L | N | L | N | L | N | L | N | L | N | L | N | L | ||
| Gender | Male | 25 | 6 | 25 | 7 | 22 | 6 | 20 | 1 | 14 | 7 | 16 | 6 | 17 | 3 | 19 | 9 | 25 | 3 | 19 | 5 |
| Female | 23 | 5 | 30 | 3 | 20 | 10 | 18 | 2 | 13 | 6 | 20 | 4 | 24 | 5 | 26 | 3 | 23 | 7 | 17 | 7 | |
| Age (yr) | > 60 | 37 | 10 | 43 | 6 | 30 | 14 | 28 | 3 | 18 | 10 | 28 | 7 | 33 | 6 | 33 | 10 | 39 | 10 | 26 | 9 |
| ≤ 60 | 11 | 1 | 12 | 4 | 12 | 2 | 10 | 0 | 9 | 3 | 8 | 3 | 8 | 2 | 12 | 2 | 9 | 0 | 10 | 3 | |
| Location | Proximal colon | 14 | 6 | 20 | 4 | 16 | 5 | 15 | 1 | 10 | 6 | 17 | 3 | 15 | 2 | 15 | 6 | 18 | 6 | 16 | 5 |
| Distal colon | 14 | 3 | 14 | 4 | 14 | 4 | 10 | 1 | 7 | 3 | 4 | 2 | 12 | 3 | 14 | 1 | 14 | 2 | 6 | 5 | |
| Rectum | 20 | 2 | 21 | 2 | 12 | 7 | 13 | 1 | 10 | 4 | 15 | 5 | 14 | 3 | 16 | 5 | 16 | 2 | 14 | 2 | |
| Gross pattern | Massive | 22 | 4 | 23 | 3 | 18 | 11 | 12 | 2 | 14 | 5 | 13 | 4 | 17 | 4 | 17 | 3 | 20 | 6 | 16 | 5 |
| Ulcerative | 17 | 5 | 24 | 3 | 15 | 4 | 19 | 1 | 9 | 5 | 13 | 5 | 19 | 4 | 18 | 6 | 20 | 3 | 12 | 5 | |
| Encroaching | 9 | 2 | 8 | 4 | 9 | 1 | 7 | 0 | 4 | 3 | 10 | 1 | 5 | 0 | 10 | 3 | 8 | 1 | 8 | 2 | |
| Size | ≥ 5 (cm) | 21 | 7 | 27 | 7 | 22 | 6 | 18 | 3 | 11 | 6 | 16 | 5 | 21 | 4 | 21 | 8 | 23 | 7 | 17 | 8 |
| < 5 (cm) | 27 | 4 | 28 | 3 | 20 | 10 | 20 | 0 | 16 | 7 | 20 | 5 | 20 | 4 | 24 | 4 | 25 | 3 | 19 | 4 | |
| LN Metastasis | LN (+) | 31 | 6 | 36 | 4 | 26 | 11 | 23 | 2 | 16 | 6 | 22 | 6 | 28 | 5 | 30 | 7 | 31 | 7 | 25 | 5 |
| LN (-) | 17 | 5 | 19 | 6 | 16 | 5 | 15 | 1 | 11 | 7 | 14 | 4 | 13 | 3 | 15 | 5 | 17 | 3 | 11 | 7 | |
| Differentiation | Well | 12 | 4 | 15 | 3 | 11 | 3 | 8 | 1 | 7 | 3 | 10 | 2 | 13 | 2 | 13 | 5 | 16 | 2 | 10 | 5 |
| Moderately | 26 | 4 | 27 | 4 | 22 | 7 | 19 | 0 | 12 | 6 | 17 | 4 | 18 | 5 | 21 | 5 | 18 | 7 | 18 | 6 | |
| Poorly | 2 | 0 | 6 | 0 | 3 | 2 | 3 | 0 | 2 | 1 | 2 | 3 | 4 | 0 | 4 | 1 | 4 | 0 | 2 | 1 | |
| Mucinous | 8 | 3 | 7 | 3 | 6 | 4 | 8 | 2 | 6 | 3 | 7 | 1 | 6 | 1 | 7 | 1 | 10 | 1 | 6 | 0 | |
| Dukes stage | A | 4 | 0 | 5 | 2 | 3 | 2 | 5 | 1 | 3 | 2 | 2 | 1 | 3 | 1 | 4 | 0 | 4 | 1 | 2 | 3 |
| B | 13 | 5 | 14 | 4 | 13 | 3 | 10 | 0 | 8 | 5 | 12 | 3 | 10 | 2 | 11 | 5 | 13 | 2 | 9 | 4 | |
| C | 22 | 5 | 26 | 4 | 18 | 9 | 18 | 1 | 12 | 4 | 15 | 5 | 21 | 5 | 21 | 6 | 23 | 6 | 17 | 2 | |
| D | 9 | 1 | 10 | 0 | 8 | 2 | 5 | 1 | 4 | 2 | 7 | 1 | 7 | 0 | 9 | 1 | 8 | 1 | 8 | 3 | |
- Citation: Zhou CZ, Qiu GQ, Zhang F, He L, Peng ZH. Loss of heterozygosity on hromosome 1 in sporadic colorectal carcinoma. World J Gastroenterol 2004; 10(10): 1431-1435
- URL: https://www.wjgnet.com/1007-9327/full/v10/i10/1431.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i10.1431