Perioperative cimetidine administration promotes peripheral blood lymphocytes and tumor infiltrating lymphocytes in patients with gastrointestinal cancer: Results of a randomized controlled clinical trial

Figure 4 Changes in CD₅₇⁺ cell percentages in perioperative period. A: at randomization; B: before operation; C: on the 2nd postoperative day; and D: on the 10th postoperative day. The difference in CD₅₇⁺ percentages between treatment and con-trol groups at time points C and D was statistically significant, ^bP < 0.01. The differences in CD₅₇⁺ percentages between treat-ment group and normal control on the 10th postoperative day was statistically significant, ^dP < 0.01.