Copyright ©The Author(s) 2015.
World J Med Genet. Aug 27, 2015; 5(3): 28-45
Published online Aug 27, 2015. doi: 10.5496/wjmg.v5.i3.28
Figure 2
Figure 2 Diagram of adeno-associated virus vector production. A: The expression cassette containing promoter, intron, target gene, and polyadenylation sequence is flanked with adeno-associated virus (AAV) inverted terminal repeats (ITRs); B: AAV rep and cap sequences without ITRs are provided in trans; C: helper virus can be adenovirus, herpes simplex virus (HSV), or baculovirus depending on the production system used. Once these three components are introduced into a host cell under proper conditions, AAV vectors will be produced.