Field Of Vision
Copyright ©2013 Baishideng.
World J Med Genet. May 27, 2013; 3(2): 5-8
Published online May 27, 2013. doi: 10.5496/wjmg.v3.i2.5
Figure 1
Figure 1 Schematic representation of the mechanism of non-allelic homologous recombination. The mechanism can occur in 3 ways. Chromosomal duplications can be created by (1) inter-chromosomal exchange; (2) intra-chromosomal exchange; and (3) intra-chromatid exchange. Although inter-chromosomal and intra-chromosomal exchanges can lead to deletions and duplications equally, intra-chromatid exchange only creates microdeletions and not microduplications. Microduplications created by non-allelic homologous recombination invariably show tandem orientations. White arrows indicate the directions of the segments. This figure is referring the report by Gu et al[6].