乙型肝炎病毒DNA聚合酶N末端蛋白基因芯片研究

表1 部分表达显著增强的基因

序号	GenBank登录号	编码蛋白	Cy5/Cy3
1	NM_006597	Homo sapiens heat shock 70kD protein 8(HSPA8), mRNA热休克70kD蛋白8(HSPA8)	3.029
2	AF070674	Homo sapiens inhibitor of apoptosis protein-1(MIHC) mRNA, complete cds凋亡蛋白1抑制剂(MIHC)	3.377
3	NM_006644	Homo sapiens heat shock 105kD(HSP105B), mRNA热休克蛋白105kD(HSP105B)	3.823
4	NM_002482	Homo sapiens nuclear autoantigenic sperm protein(histone-binding)(NASP), mRNA核自身抗原精蛋白(结合性组蛋白)(NASP)	4.553
5	NM_014887	Homo sapiens hypothetical protein from BCRA2 region(CG005), mRNA	4.602
6	AK055725	Homo sapiens cDNA FLJ31163 fis, clone KIDNE1000050	5.212
7	NM_003276	Homo sapiens thymopoietin(TMPO), mRNA促胸腺生成素(TMPO)	6.171
8	M11952	Human T-cell receptor rearranged beta chain gene V-region(V-D-J)V-beta-ATL12-2 T细胞受体重新排列b链可变区	10.280

表2 部分表达显著降低的基因

序号	GenBank登录号	编码蛋白	Cy5/Cy3
1	NM_005627	Homo sapiens serum/glucocorticoid regulated kinase(SGK), mRNA 血清/糖皮质激素调节激酶(SGK)	0.097
2	NM_001961	Homo sapiens eukaryotic translation elongation factor 2(EEF2), mRNA真核翻译延伸因子2(EEF2)	0.131
3	NM_001417	Homo sapiens eukaryotic translation initiation factor 4B(EIF4B), mRNA真核翻译起始因子4B(EIF4B)	0.228
4	NM_003641	Homo sapiens interferon induced transmembrane protein 1(9-27) (IFITM1), mRNA干扰素诱导的跨膜蛋白1(9-27)	0.287
5	NM_005954	Homo sapiens metallothionein 3 (growth inhibitory factor(neurotrophic))(MT3), mRNA金属硫因3(生长抑制因子)(MT3)	0.327
6	NM_002415	Homo sapiens macrophage migration inhibitory factor(glycosylation-inhibiting factor)(MIF), mRNA巨噬细胞移动抑制因子(糖基化抑制因子)(MIF)	0.375
7	NM_001551	Homo sapiens immunoglobulin (CD79A) binding protein 1(IGBP1), mRNA(IGBP1)免疫球蛋白(CD79A)结合蛋白1	0.382
8	NM_003789	Homo sapiens TNFRSF1A-associated via death domain(TRADD), mRNA TNFRSF1A相关的死亡域(TRADD)	0.391