Artificial intelligence-driven decoding of trajectories of cancer cell plasticity: A paradigm shift in oncological assessment and treatment

Figure 1 Schematic representation of hierarchy model and stochastic model of tumorigenesis. This figure was prepared on power point and Canva. Two foundational models of tumorigenesis explain the origin and growth of tumors as well as maintenance of cellular diversity. Hierarchy model proposes the ability of only specialized subpopulation of cells to drive the tumor development. The stochastic model argues that any cell has an equal and random chance to promote tumor development. CSC: Cancer stem cell.