Comparison of clinical efficacy and postoperative inflammatory response between laparoscopic and open radical resection of colorectal cancer

Table 1 Comparison of perioperative conditions between the two groups (mean ± SD)

Groups	Cases	Operating time (min)	Intraoperative blood loss (mL)	Recovery time of gastrointestinal function (h)	No. of lymph node dissections (bout)	Hospital stay (d)
Study group	48	186.18 ± 33.54	111.34 ± 21.45	25.35 ± 4.55	15.19 ± 3.04	10.09 ± 2.38
Control group	48	129.38 ± 26.83	163.77 ± 32.41	36.06 ± 7.13	16.20 ± 298	13.51 ± 3.66
t		9.162	9.346	8.773	1.643	5.427
P		0.000	0.000	0.000	0.104	0.000

Table 2 Comparison of inflammatory response index levels before and after the operation between the two groups (mean ± SD)

Time	Groups	Cases	CRP (mg/L)	IL-6 (ng/mL)	IL-8 (ng/L)	IL-10 (ng/L)
Before the operation	Study group	48	7.98 ± 2.33	9.79 ± 4.11	3.79 ± 1.71	48.96 ± 12.51
	Control group	48	8.29 ± 2.60	10.56 ± 3.78	4.08 ± 1.45	50.13 ± 11.67
	t		0.615	0.955	0.896	0.474
	P		0.540	0.342	0.373	0.637
After the operation	Study group	48	14.91 ± 5.56	19.11 ± 6.68	12.61 ± 3.69	36.48 ± 9.39
	Control group	48	21.79 ± 7.33	34.03 ± 9.40	16.67 ± 4.54	28.39 ± 7.61
	t		5.181	8.964	4.808	4.637
	P		0.000	0.000	0.000	0.000

CRP: C-reactive protein; IL: Interleukin.

Table 3 Comparison of pain stress response indexes before and after operation between the two groups (mean ± SD)

Time	Groups	Cases	NPY (g/L)	PGE2 (ng/L)	5-HT (ng/L)
Before the operation	Study group	48	109.79 ± 13.46	269.54 ± 37.34	151.70 ± 18.86
	Control group	48	113.29 ± 15.01	273.91 ± 40.04	148.85 ± 20.45
	t		1.203	0.553	0.710
	P		0.232	0.582	0.480
After the operation	Study group	48	153.13 ± 16.91	313.76 ± 40.64	218.78 ± 22.65
	Controlgroup	48	178.68 ± 20.51	369.78 ± 44.37	267.64 ± 30.74
	t		6.659	6.450	8.865
	P		0.000	0.000	0.000

NPY: Neuropeptide; PGE2: Prostaglandin E2; 5-HT: 5-hydroxytryptamine.

Table 4 Comparison of the incidence of complications between the two groups, n (%)

Groups	Cases	Anastomotic leakage	Ileac passion	Infection of incisional wound	Deep vein thrombosis	Total incidence rate
Study group	48	1 (2.08)	0 (0.00)	1 (2.08)	0 (0.00)	2 (4.17)
Control group	48	3 (6.25)	2 (4.17)	3 (6.25)	1 (2.08)	9 (18.75)
χ2						5.031
P						0.025