Short-term outcomes of radiofrequency ablation for hepatocellular carcinoma using cone-beam computed tomography for planning and image guidance

Table 3 Prognostic factors and predictors of disease progression according to Cox regression analysis

Variable	mTTP (mo)	Univariate analysis	Cox proportional hazards model (multivariate analysis)
		P value	HR	P value	95%CI
Sex		0.246
Male	12.9
Female	6.0
Age (years)		0.001	1.052	0.036	1.003-1.103
< 58	35.2
≥ 58	11.1
Tumour size (cm)
< 2	-	< 0.001
≥ 5	9.7	0.468
Tumour adjacent to the aorta, diaphragm, or digestive tract		0.189
Yes	13.9
No	9.7
Barcelona Clinic Liver Cancer stage		0.010
A	35.2
B	11.1
mRECIST–Post-RFA		0.003	4.080	0.021	1.231-13.524
CR	14.1
PR	6.4

mTTP: Median time to progression; HR: Hazard ratio; RFA: Radiofrequency ablation; CR: Complete response; PR: Partial response.