Immediate implant placement in combination with platelet rich-fibrin into extraction sites with periapical infection in the esthetic zone: A case report and review of literature

Figure 3 Representational images and illustrations describing each step of covering the barrier membrane. A: Platelet-rich fibrin (PRF) clots were obtained into the test tube through whole blood centrifuged immediately at 3000 rpm for 10 min; B: PRF clot was mixed with 0.25 g bone substitute (Bio-Oss) then placed on the implant and the bone defect; C: A piece of PRF clot was pressed into a membrane by sterile gauze and placed on the surface of Bio-Oss-PRF mixture; D: Placement of collagen membrane; E: The other PRF membrane was placed on the surface of the collagen membrane; F: Tension-free suture.