Association between neutrophil-to-lymphocyte ratio and major postoperative complications after carotid endarterectomy: A retrospective cohort study

Table 1 Characteristics of the patients at baseline

	Total	WOPC group	PC group	P
No. of cases	206	166	40
Age (yr)	62.0 ± 7.2	61.6 ± 7.3	63.5 ± 6.8	0.151
Sex				0.616
Male	175 (84.95%)	140 (84.34%)	35 (87.50%)
Female	31 (15.05%)	26 (15.66%)	5 (12.50%)
BMI (kg/m2)	25.33 ± 2.89	25.25 ± 2.85	25.63 ± 3.04	0.461
Smoking history	118 (57.56%)	97 (58.79%)	21 (52.50%)	0.470
ASA grade				0.521
Grade II	157 (81.07%)	136 (81.93%)	31 (77.50%)
Grade III	39 (18.93%)	30 (18.07%)	9 (22.50%)
Preoperative combined diseases
Hypertension	146 (70.87%)	114 (68.67%)	32 (80.0%)	0.157
Diabetes mellitus	74 (35.92%)	61 (36.75%)	13 (32.50%)	0.615
Heart disease	56 (27.18%)	40 (24.10%)	16 (40.0%)	0.042a
Respiratory disease	11 (5.34%)	10 (6.02%)	1 (2.50%)	0.374
Neurological disease	96 (46.60%)	78 (46.99%)	18 (45.0%)	0.821
Kidney disease	4 (1.94%)	4 (2.41%)	0	0.321
Degree of carotid artery stenosis on the surgical side				0.449
Mild/moderate stenosis	3 (1.46%)	2 (1.20%)	1 (2.5%)
Severe stenosis	201 (97.57%)	163 (98.19%)	38 (95.0%)
Occlusion	2 (0.97%)	1 (0.60%)	1 (2.50%)
Degree of carotid artery stenosis on the contralateral side				0.146
Mild/moderate stenosis	169 (85.35%)	132 (83.02%)	37 (94.87%)
Severe stenosis	21 (10.61%)	19 (11.95%)	2 (5.13%)
Occlusion	8 (4.04%)	8 (5.03%)	0
Operating time (min)	141.33 ± 40.96	138.39 ± 38.78	153.57 ± 47.62	0.129
Duration of carotid artery occlusion (min)	22.00 (18.0–44.0)	22.00 (17.0–43.0)	27.0 (18.50–49.50)	0.328
Anesthesia method
TIVA	163 (79.13%)	129 (77.71%)	34 (85.0%)	0.309
Combined intravenous–inhalation anesthesia	43 (20.87%)	37 (22.29%)	6 (15.0%)
Intraoperative intake and output volume (mL)	897.57 ± 333.40	911.85 ± 331.01	839.75 ± 341.01	0.221
meanSBP	128.82 ± 12.92	128.37 ± 12.77	130.69 ± 13.54	0.309
SDSBP	20.26 ± 4.91	20.09 ± 5.01	20.93 ± 4.48	0.333
CVSBP	0.16 ± 0.04	0.16 ± 0.04	0.16 ± 0.03	0.550
meanDBP	69.61 ± 7.83	69.80 ± 7.77	68.82 ± 8.14	0.480
SDDBP	10.23 ± 2.70	10.18 ± 2.81	10.42 ± 2.26	0.612
CVDBP	0.15 ± 0.04	0.15 ± 0.04	0.15 ± 0.04	0.372
Intraoperative use of vasopressors	84 (40.78%)	65 (39.16%)	19 (47.50%)	0.335
Intraoperative use of antihypertensive agents	73 (35.44%)	63 (37.95%)	10 (25.0%)	0.124

^aP < 0.05, statistically significant difference was observed between two groups.

ASA: American society of anesthesiologists; BMI: Body mass index; CEA: Carotid endarterectomy; CV_DBP: Coefficient of variation in diastolic blood pressure; CV_SBP: Coefficient of variation in systolic blood pressure; mean_DBP: mean diastolic blood pressure; mean_SBP: mean systolic blood pressure; PC: Post-CEA complications; SD_DBP: Standard deviation of diastolic blood pressure; SD_SBP: Standard deviation of systolic blood pressure; TIVA: Total intravenous anesthesia; WOPC: Without post-CEA complications.