Clinical features and survival of patients with multiple primary malignancies

Table 3 Univariate analysis and multivariate analysis of the prognostic factors of overall survival in patients with two malignancies

Factors	Cases	Univariate analysis		Multivariate analysis
		Median OS in mo	P	HR	95%CI	P
Gender			0.114
Male	119	31.2
Female	103	37.1
Age at second cancer (yr)			0.038	1.016	1.000-1.032	0.046
≤ 65	128	36.4
> 65	94	28.4
Metastasis			0.000	4.291	2.743-6.710	0.000
No	123	86.9
Yes	99	20.4
MPM			0.809
Synchronous	51	36.4
Metachronous	171	35.3

MPM: Multiple primary malignancies; OS: Overall survival.